Plasma Potentially able to Boost Survival Rate of Coronavirus patients

A new study of patients hospitalized with COVID-19 says that the technique of plasma transfusions could improve the survival rates if they’re done early enough. 

While this did happen at New York Mt. Sinai’s hospital, it hasn’t undergone the normal peer review process that’s needed for publication within medical or scientific resources. But during the coronavirus emergency, many researchers are giving out the results when they can get them.  About 18% of patients who had the plasma ended up worsening, but the 24% of those who did get it ended up getting better with time.

After 16 days, 13% of the recipients died, which is compared to the 24% of the controlled ones.  72% of them were discharged compared to the 67% in the control group. So it did conclude that this could be a potentially efficacious treatment for those with COVID-19, but there is some data that suggests that the non-intubated patients might benefit more than those who need ventilators.

However, this does come with one caveat and that this is a retrospective case controlled study, and it doesn’t have the rigor that the randomized controlled testing will need to be done.  But this does show some promise that the plasma is effective as a solution.  This is an approach that might provide the first solid data for those who wat to protect themselves against this disease.

This is also in comparison to other treatments for example, hydroxychloroquine and remdesvir.  These were other treatments that would supposedly help with fighting this disease, but that isn’t the case.  The plasma variant has a much higher improvement in survival compared to these other drugs.

However, there was no significant improvement for the intubated patients before this therapy, but that might be because the lung damage was too severe to respond to the treatment that is happening.  That means that it may not work for those who need ventilation, and an alternative solution needs to be found in that case.

This was originally raised in March when a paper published it, since this was a procedure that was used during the polio, influenza, measles, and mumps outbreaks. It was also used during H1N1 along with the Ebola epidemic to decent results.

While every virus and disease is of course different, this does provide a reassuring and useful possible hope during all of this happening right now.  This might be good as well for developing plasma treatments too over time.

While the latest study is promising, experts do advise against the search for a treatment that’s quick for it, since they don’t want a repeat of the other drugs where it was used without any evidence of efficacy and safety, thereby making this worse.  They don’t want this to be a flavor of the month treatment, but instead something that could potentially help those who want a legitimate coronavirus treatment.

We have to wait and see though if this works. While there is a lot of research being done, they’re working as fast as they can to stop this mass pandemic from getting worse.

Moderna’s Vaccine Trial Shows Participants Developed Antibodies to COVID-19.

There were some volunteers who received the COVID-19 vaccine from Moderna that proved positive in results.  These guys partnered with the national institutes of health to create a vaccine.  If this goes well, this could possibly be available to the public as early as January, which is good news, and something that people have been waiting for.  This of course, comes from the phase 1 trial, which shows a small number of people and focuses on whether the vaccine gets an immune response and is of course safe.  They haven’t been peer reviewed por published yet in terms of results though.

Moderna is a company based in Massachusetts and is one of the eight different developers worldwide doing clinical trials for humans with a vaccine placed against the virus.  There are two others that are in the US, and one in Britain, and four in China.  Moderna has vaccinated many study participants and looked at the antibodies in eight of them. All eight had neutralizing antibodies to the virus at levels that are higher in those who have naturally recovered from COVID-19 according to studies.  The antibodies bound to the virus and disabled from the human cells.  This of course shows that these antibodies are able to block the virus, and this is one of the first steps to creating a vaccine.  A vaccine specialist that isn’t involved in Moderna does think this is great, since not only does it show the antibody is working, but it also prevented the virus from infecting the other cells that are there as well.

However, while it does have good results in the lab, it isn’t known if it’ll protect the people from the virus in the real world.  This is to begin the phase 2 trials, which typically involve about a few hundred people, and of course the large scale trials will be in July. These can involve tens of thousands of people.

It was said before the pandemic that vaccine developers would normally test this out on thousands before phase 3, but its extremely unlikely to have that many before July, since only a few dozens have been vaccinated so far.  It makes sense of Moderna to move to phase 3 without vaccinating a ton of people since there are thousands that die every single day.  It’s different, and time of course of the essence.

Dr. Fauci of the national Institute for Allergy and Infectious Disease actually side it would take 12-18 months for a vaccine to be on the market, but with an estimate for the vaccine, it does put that right on the delivery date of hi estimation next year.

In the study, three participants did have the symptoms of a fever and flu, and it was when they got the vaccine at around 250 micrograms.  Some will anticipate the phase 3 study will be smaller than that.  So far, the study subjects were vaccinated at a smaller level than the first one, and in most cases, the antibodies were higher than those who naturally got the coronavirus. But it isn’t clear whether the natural infection confers the immunity, so it’s not clear whether this will confer the immunity.  The thing is, we don’t know yet, but there is a chance for a vaccine every single day.

How to Keep Yourself Healthy At All Times

Do you wear a face mask? Do people stay at least 6 feet away from you? Do you touch things with your hands? Well, as the lockdown restrictions ease and cities reopen, you might want to change how you go to places.  The risk won’t go away, but until herd immunity happens or we have a vaccine, we should be careful. Since it can be passed by those who are asymptomatic and it’s highly contagious, it’s imperative to stay alert, and here is how.

First, don’t get too comfy. While the causes and deaths are going up and down, plenty of leaders are saying that the growth rates are slowing down in pockets, but there could be a second wave of infection. If we pull back too soon, there might be a second wave that is much worse. Even as nonessential businesses and public places open up again, you have to remember that this hasn’t disappeared. Just because the restrictions are lifting doesn’t mean you won’t get it.  You should think twice about what to do once this ends.

Wearing a face mask is something that you should definitely consider. While it is a voluntary healthy measure in places with large transmission rates and in places where you can’t maintain social distancing, some places are making it mandatory, such as in the stores.  If you’re taking a walk, you should try to keep a face covering on, so you don’t avoid the side eye or the lectures in stores.

Next, don’t make shopping trips a form of entertainment.  Sure it’s boring, but the symptoms of COVID-19 are scary and for people who have it it can take weeks to recover.  You don’t want this, and you should limit our exposure to others.  You should get what you get and not browse the aisles as well.

If you’re still using your hands to press buttons for the walk signs and such, you need to stop.  You should try to use a different body part for this.  you should learn to tap out the PIN codes with your knuckles instead of your fingertips. Learn to open up doors with your shoulders, feet, or even hips.  You can use sleeves and jackets as well to open up things too. Consider using your clothes as well that you can wash so that you don’t have to expose your skin to this either.

Finally, continue to keep your distance, and keep a boundary between you and others when you do go out.  You should keep that six feet boundary whenever possible, and try to go on bikes and such, and keep picking up food to go.  The more distance that you give, the better it’ll be, and it can be a way to keep you away from others and potentially getting infected.

While it can be hard, making sure you set aside reusable bags is a good thing to do.  You can’t really reuse them now but washing anything that comes into your house is a good thing.

While this whole thing has changed the way society is, it definitely is something that you want to keep in mind, and something you should definitely watch out for, for your own health and safety.

COVID-19 Prevention Tips and Strategies

The new coronavirus is an infection that can lead to COVID-19.  It’s a respiratory infection, and it can spread and cause life-threatening issues in some people. It does survive in the air and on various surfaces long enough to infect people, and it does multiply faster in the body than other viruses even if you’re now showing symptoms, and you can pass on the virus without symptoms at all.

Some have mild to moderate symptoms, but you can never be too careful, and in this article, we’ll highlight some important preventative tips for you.

First, was your hands carefully and frequently.  Lather the wrists, between your fingers, and under the fingernails. You can use an antibacterial along with an antiviral soap. Also, consider using hand sanitizer too. Make sure to wash your hands a few times each day, especially after touching your phone or laptop.

Try to avoid touching your face as much as you can, since the virus can live on harder surfaces for up to 72 ours, so make sure to not touch your face, and avoid biting the fingernails.

You also shouldn’t be touching anyone right now.  Don’t be the reason someone gets this.  shaking hands and hugging others will spread this.

Don’t share personal items.  Try not to share straws and eating utensils.  Try to use reusable straw, cups, and other dishes, and try to keep it to just one person.

Make sure to cover your nose and mouth when you sneeze. This is usually how it travels, and it can land and be there for up to three days.  Use a tissue or sneeze into the elbow and then keep your hands as clean as possible. Wash your hands carefully regardless, but do so more now.

Make sure to clean and disinfect the surfaces you use. This can live there for a few days, so make sure that the door handles, countertops, toys, furniture, and even your phone and other devices should be cleaned too. Disinfect areas once you’ve finished bringing in groceries. Use white vinegar or hydrogen peroxide solutions for better cleaning and disinfecting surfaces.

Make sure to also take social distancing seriously. It can be found in your spit, and it can happen even if you don’t have symptoms. Stay home and work remotely whenever you can.  If you must do this, keep a distance of 6 feet from others, and you can transmit this by steaking to a person in close contact with you.

With that, also don’t gather in groups.  This can cause the spread to move faster and further, and you should try to avoid any place where you might sit or stand too close to another person.

Finally, try to avoid eating or drinking in other places.  It isn’t’ time to go out to eat, so you should avoid the eateries.  This can be transmitted through food and silverware, and it might be airborne too.  You can still get delivery or takeout food, and make sure that you can cook this thoroughly and make sure it can be reheated.  You should avoid cold foods as much as possible, and of course, food from salad bars and buffets.

Finally, if you are sick, make sure to stay away from others, and call your doctor if you do have symptoms. Do make sure to wash a mask too.

This is very important to do, and if you want to prevent others from getting sick and flattening the curve, this is a good way to do it.